Endocrine Abstracts

Aims: The short synacthen test (SST) is considered as the gold standard test to assess the viability of the hypothalamic-pituitary-adrenal axis. This study explores the appropriateness of its clinical use in a district general hospital. Furthermore, it assesses the effectiveness of the alternate use of 9AM cortisol in excluding hypoadrenalism and the cost-effectiveness of sampling both 30 and 60 minutes serum cortisol in SST.Me...

Aims: The short synacthen test (SST) is considered as the gold standard test to assess the viability of the hypothalamic-pituitary-adrenal axis. This study explores the appropriateness of its clinical use in a district general hospital. Furthermore, it assesses the effectiveness of the alternate use of 9AM cortisol in excluding hypoadrenalism and the cost-effectiveness of sampling both 30 and 60 minutes serum cortisol in SST.Me...

Case history: A 39 year old lady was referred to endocrinology with hirsutism. In the clinic, the pattern of hair growth was confirmed as androgenic, she had cliteromegaly and family members had commented on her voice deepening. She underwent menarche at 13 years old, has menorrhagia and has had hirsutism her entire adult life that had recently worsened. Her biochemistry confirmed hyperandrogenism with non-suppressed LH/FSH. At her second appointment after serious pathology ha...

Introduction: Within our single centre, the referral rate from the endocrine hypertension clinic to the sleep clinic is high. We have also observed a particular metabolic profile of those patients including raised normetanephrines which subsequently improve after treatment for sleep apnoea.Illustrative cases: 56 year old man with a BMI of 33 kg/m2 and multiple complications of obesity including NAFLD, gallstones and loss of libido. He was rare...